Trafficking in Persons (TIP), also known as modern slavery, is a serious crime and human rights violation that involves the non-consensual exploitation of men, women, and children for sex work, forced labor, forced marriage, organ removal, forced begging, and/or other ends. All of these forms of trafficking are present in Latin America and the Caribbean. Women, children, and marginalized populations such as migrants, LGBTI individuals, and indigenous peoples are particularly vulnerable to trafficking. As such, prevention of trafficking in persons necessarily requires a gender focus and intersectional approach that fosters inclusion and empowerment of women and marginalized populations to create solid foundations that serve as a vector for lasting social change.